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The BIOFIRE System and Your Immune System The BIOFIRE System provides syndromic infectious disease testing empowering healthcare providers to select the most appropriate test the first time Patients benefit from quicker diagnosis and more targeted treatments Clinicians benefit from a better stewardship of antibiotics Labs improve efficiency and cost savings The BioFire Pneumonia Plus Panel PN panel analyzes native sputum including miniBAL endotracheal lavage and bronchoalveolar liquids including mini BAL for 33 clinically significant pathogens and resistance genes to antimicrobials within an hour Respiratory The burning of biomass including wood plants and other organic materials produces gaseous pollutants and fine particles that negatively affect the respiratory system Climate change may make it more difficult to reverse the negative effects of forest fires on human health In the United States wildfire smoke is associated with hospitalizations caused by respiratory diseases like asthma COPD and lung cancer Additionally this kind of air pollution can be an underlying risk factor for cardiovascular diseases and is a significant contributor to the burden of illness for the most vulnerable population that include those with lower socioeconomic status SES Wildfires have led to unhealthy levels of air pollutants in many communities during the COVID19 epidemic However the response of public health officials to this environmental issue is sporadic and mainly focused on educating people about the management of symptoms This knowledge gap is concerning given the evidence of potential health hazards from the continued exposure to smoke and other sources of poor air quality Researchers are now evaluating the best way to safeguard publics health during future incidents of this type NIH is funding research into this crucial public health issue through the BLUE CORAL study as well as its successor FIRE CORAL For the first time the study is a prospective cohort study that will examine longterm effects resulting from exposure to smoke from wildfires and other sources FIRE CORAL enrolls adults who are hospitalized for COVID19 index episodes and speak English or Spanish however they are not pregnant The protocol for FIRE CORAL includes a series of tests inperson that objectively measure pulmonary function testing and lung imaging as well as functional assessment Smoke and other particles can trigger or worsen respiratory problems like emphysema COPD and pneumonia Smoke exposure can cause adverse effects on your health To lessen or stop these effects avoid outdoor activities and use the EPA N95 mask The mask is designed to trap fine particles Smoking can cause irritation to the eyes and throat and cause the nose to run To lessen the effects the lungs must be flushed by drinking lots of fluids and taking medications that decrease inflammation like corticosteroids Bloodstream Your bloodstream is on the front lines of fighting germs that invade your body Dendritic cells which are special cells are like your fire departments call centre they gather antigens molecules that trigger an immune response from invaders and then release proteins that trigger other white blood cells to come fight them The white blood cell counts differentials and band cells were boosted during firefighters firefighting shifts compared with levels following physical exertion without firefighting Skin As the wildfires in California produced smoke and ash into the air this past fall and winter dermatologists were concerned how this could affect the skin of people exposed to it Maria Wei is a graduate student from University of California Irvine She examines how extreme wildfire pollution affects the skin Her research was published in Scientific Reports on April 22nd Weis study shows that the temperature of the skin changes depending on the length of time the body has been exposed It can take as long as two hours for the skin to reach its flash point the point at which it burns and then turns ashy This is why its crucial to not stay near a fire or campfire and why you must wear protective clothing when you are outside during a forest fire or even a hot day Forest fires will continue occur despite the measures implemented to reduce the risk of wildfire pollution Wei predicts that as climate change causes forests to burn faster the number of people suffering from wildfires will increase This means that more people will need to wear hats and long sleeves as well as thick moisturizers Its also worth knowing that atopic dermatitis itchy skin that a lot of people suffer from can be made worse by the air pollution from wildfires She claims that the particles in smoke can block pores and cause atopic skin to become worse Another issue is that atopic dermatitis tends to make people more sensitive to UV light which can be aggravated by wildfire smoke This can cause people to be more likely to visit tanning salons and it may cause them to tan with less protection than they need to A treatment with ice and fire can help reduce atopic skin symptoms of dermatitis however it isnt advised for anyone who has an open wound or rash bio ethanol inset fire fireplacesandstove who have active acne should avoid it as well and if youre breastfeeding or pregnant it is recommended to avoid this treatment completely The IS Clinical Fire Ice Facial at Novuskin Las Vegas top membership MedSpa Its a highly effective resultsdriven facial that bridges the gap between a mild facial and a peel without requiring any downtime Its designed to rejuvenate skin improve rosacea and reduce acne scarring and fine lines and stimulate cellular renewal Its an incredible treatment to give yourself an energizing glow Infections The human body is made up of a complex system of organs and tissue that work together in order to guard against infections Infections can be caused by microorganisms such as bacteria viruses and parasites which infect healthy cells and cause them to multiply in uncontrolled ways When this occurs your immune system may respond by displaying symptoms of illness These symptoms could range from a runny nose to a stomach that is upset as well as swelling of lymph glands or a rash Your symptoms can be affected by the nature of the infection its location and even your temperature Infections can spread through different ways but they are most often spread through airborne droplets that remain after sniffling or coughing Bacterial diseases such as tuberculosis and strep throat meningococcal disease and Legionnaires disease spread in this manner as do some viral infections like the common cold and influenza Certain bacterial infections such as skin infections or sexually transmitted diseases STIs such as Chlamydia and gonorrhea can be transmitted through direct contact with affected tissues or mucous surfaces or indirectly through surfaces that are contaminated Some bacterial infections are spread by insects such as fleas ticks or mosquitoes Viruses parasites and other microorganisms are small enough to enter your bloodstream to infect your cells This can lead to serious diseases such as the common cold or AIDS Fungi can cause skin problems like athletes feet and ringworm while others infect the respiratory tract and nervous system The BioFire Panel uses our innovative FilmArray Technology to test the sputum and bronchoalveolar fluid samples to provide a complete list of pathogens that are involved in upper respiratory infection The kit includes a reagent bag that contains all the chemistry needed to perform reverse transcription nested multiplex PCR and detection with a single machine This is a simple solution that helps clinicians identify and treat patients with a variety respiratory symptoms This test has received an Emergency Use Authorization and is available through bioMerieuxs CLIA moderate and high complexity labs

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