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Congenital triangular alopecia CTA is a benign asymptomatic nonprogressive localized and noncicatricial type of alopecia that is usually first noted during infancy or childhood The pattern of hair loss is traditionally described as triangular oval or lancet shaped with apex toward the vertex We present a case series of CTA located in unusual sites We performed trichoscopy in 78 patients with CTA From this group we selected 10 individuals 4 males and 6 females whose disease was not localized on the typical scalp area The alopecic area was located on the occipital region in 5 patients the parietal region in 4 patients at the vertex in 1 With trichoscopy vellus hairs were detected in all patients and evidence of empty follicles was noticed only in 3 patients In contrast with the preconceived notion that all CTAs are frontotemporal our case series points out that this disease could be localized in other scalp sites In contrast with the preconceived notion that all CTAs are frontotemporal our case series points out that this disease could be localized in other scalp sites Dermoscopy is a tool that aids clinicians in the diagnosis of actinic keratosis however few diagnostic accuracy studies have determined its sensitivity and specificity for this diagnosis Determine the diagnostic accuracy of dermoscopy on actinic keratosis A systematic review was conducted on EMBASE PubMed Scopus and the Cochrane Central Registry of Controlled Trials from inception to August 2019 We screened 485 titles and abstracts Two studies comprising 219 actinic keratoses were eligible for qualitative analysis The number and heterogeneity of included studies limited a quantitative analysis Studies that focus specifically on the diagnostic accuracy of dermoscopy for actinic keratosis are lacking Studies that focus specifically on the diagnostic accuracy of dermoscopy for actinic keratosis are lacking Bullous pemphigoid BP is a subepidermal blistering disorder caused by autoantibodies directed against hemidesmosomal proteins Many patients with BP demonstrate circulating IgE autoantibodies Although the role of IgE in the pathogenesis of BP is unknown a correlation between IgE antibodies and eosinophilia has been observed Soluble CD23 and galectin3 are the main elements of the IgE group The roles for CD23 in BP as a potential biomarker and IgE production regulator have been characterized but no studies have evaluated any roles for galectin3 in this disease In this study we evaluated galectin3 expression in BP as a first step in assessing its role in the pathogenesis of this autoimmune blistering process Sixty specimens diagnosed as BP were stained with antibodies to galectin3 The percentages of nuclear and cytoplasmic galectin3 expression and staining intensity were evaluated There was a significant difference in galectin3 cytoplasmic and nuclear expression within keratinocytes imm of this observed loss on disease pathogenesis The skin is often seen as a world apart but not rarely do cutaneous manifestations reveal signs of systemic disease The aim of this review is to include in one paper all the possible correlations between nephrological and dermatological manifestations of the same disease in pediatric patients while also keeping in mind that in apparent exclusively dermatological diseases there can be nephrological manifestations as part of the same disorder and vice versa We searched on PubMed for a possible link between skin and kidney matching the following terms and correlated MeSH terms dermatology skin kidney renal disease nephrology pediatrics child childhood vasculitis and cancer We selected only articles reporting a link between nephrology and dermatology in pediatrics and they are all included in this comprehensive review Kawasaki disease HenochSchönlein purpura systemic lupus erythematosus Dent disease subcutaneous fat necrosis Langerhans cell histiocytosis renal cell carcinoma nonHodan exclusively dermatological disease there can be nephrological manifestations as part of the same disorder and vice versa Atopic dermatitis AD a chronic recurrent inflammatory skin condition primarily affects children Topical treatment systemic treatment and phototherapy are mainstays of treatment Topical corticosteroids TCS are firstline therapy for AD but are associated with various adverse effects Topical calcineurin inhibitors TCI can be used as an alternative to TCS The aim of the study is to compare the efficacy of topical preparations of fluticasone and tacrolimus in reducing the severity of disease and to assess the quality of life QoL and to estimate if any association exists between severity of disease and QoL Thirtyseven children with AD randomly received one of the 2 topical treatments with daily application for the first 4 weeks in the acute phase and twice weekly for next 4 weeks in the maintenance phase The severity of disease was assessed using SCORing Atopic Dermatitis SCORAD and QoL was assessed using the Childrens Dermatology Life Quality Index CDLQI At the end of the acute phase there was a reduction in SCORAD score of 6929 in the fluticasone group and 642 in the tacrolimus group P 0001 In the maintenance phase the score had risen in the fluticasone group by a mean difference of 081 while in the tacrolimus group it decreased by 099 Both fluticasone and tacrolimus groups improved in childrens QoL P 0001 Positive correlation r 04668 exists between SCORAD and QoL The most common adverse skin reaction noted was skin burning with tacrolimus Fluticasone and tacrolimus are equally efficacious in the treatment of AD and have similar benefits with childrens QoL Tacrolimus is better than fluticasone at reducing the extent of lesions Fluticasone and tacrolimus are equally efficacious in the treatment of AD and have similar benefits with childrens QoL Tacrolimus is better than fluticasone at reducing the extent of lesionsSkin hair and nail supplements sometimes referred to as beauty supplements or ingestible skin care are a large and growing industry selleck products These products may contain vitamins and minerals sometimes in very high doses They may also contain herbs hormones microbes or animal derivatives such as fish oils and collagen powders Dietary supplements are regulated as foods not as drugs by the US Food and Drug Administration FDA Therefore manufacturers do not need to provide any proof of safety efficacy or quality prior to sale This is of serious concern as many adverse effects due to supplement components have been reported The potential risks cover multiple categories These include acute toxicities such as choking as well as chronic toxicities such as increased risk of diabetes Teratogenicity and interactions with drugs and laboratory testing have been documented in research studies Other risks include potentially increased risk of cancer with longterm use allergic reactions and others It is vital that physicians educate their patients on these risks