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The original version of the article unfortunately contained an error in the first name and the surname of the all authors in the author group Below is the corrected first name and the surname of the authors Obstructive sleep apnea OSA has gastrointestinal implications as it is associated with gastroesophageal reflux disease Less certain is an independent association between OSA and Barretts esophagus We performed a systematic review and metaanalysis to evaluate the association between OSA and Barretts esophagus A systematic search of Ovid MEDLINE Embase Web of Science CINAHL and the Cochrane Central Register of Controlled Trials was performed Inclusion criteria were observational studies retrospective and casecontrol assessing the association between OSA and Barretts esophagus in adult subjects Data from the included studies were extracted and used to calculate the pooled odds ratio of OSA with 95 confidence interval CI between patients with Barretts esophagus and those without using a randomeffects model Altogether six studies involving 2333 subjects met the inclusion criteria and were included in this metaanalysis The pooled analysis found a significantly increased risk of OSA high risk of OSA and patientreported OSA symptoms among patients with Barretts esophagus versus those without Barretts esophagus with a pooled odds ratio OR of 219 95 CI 153315 A subgroup analysis for cases of definite OSA formally diagnosed via polysomnography and Barretts esophagus n  2 studies also demonstrated significant association OR 259 95 CI 139484 A significantly increased risk of OSA among patients with Barretts esophagus was demonstrated in this metaanalysis Further investigation is warranted to determine the pathophysiology and clinical implications of this association A significantly increased risk of OSA among patients with Barretts esophagus was demonstrated in this metaanalysis Further investigation is warranted to determine the pathophysiology and clinical implications of this associationThe diverse human gut microbiome is comprised of approximately 40 trillion microorganisms representing up to 1000 different bacterial species The human microbiome plays a critical role in gut epithelial health and disease susceptibility While the interaction between gut microbiome and gastrointestinal pathology is increasingly understood less is known about the interaction between the microbiome and the aerodigestive tract This review of the microbiome of the aerodigestive tract in health and alterations in microbiome across esophageal pathologies highlights important findings and areas for future research First microbiome profiles are distinct along the aerodigestive tract spanning the oral cavity to the stomach In patients with refluxrelated disease such as gastroesophageal reflux disease Barretts esophagus and esophageal adenocarcinoma investigators have observed an overall increase in gram negative bacteria in the esophageal microbiome compared to healthy individuals However whether differences in microbiome promote disease development or if these shifts are a consequence of disease remains unknown Interestingly use of proton pump inhibitor therapy is also associated with shifts in the microbiome with distinct shifts and patterns along the aerodigestive tract The relationship between the human gut microbiome and esophageal pathology is a ripe area for investigation and further understanding of these pathways may promote development of novel targets in prevention and therapy for esophageal diseases The Viatorr Controlled Expansion VCX stentgraft was designed to mitigate hepatic encephalopathy HE after transjugular intrahepatic portosystemic shunt TIPS creation To determine the incidence and degree of HE after VCX TIPS Thirtythree patients MF 1716 mean age 58years mean MELD score 12 who underwent VCX TIPS between 2018 and 2019 were retrospectively studied 1133 33 patients had medically controlled preTIPS HE TIPS indications included variceal hemorrhage n  12 30 and ascites n  21 70 Measured outcomes were postTIPS HE overall recurrent de novo graded using the West Haven system timetoHE occurrence HErelated hospitalization rate and TIPS reduction rate VCX TIPS were 8 mm in 2833 85 and 10 mm in 533 15 Erastin cell line Mean final portosystemic pressure gradient was 6mmHg Cumulative HE incidence postTIPS was 61 2033 1 3 6 and 12month HE rates were 24 30 53 and 61 over 247day median followup Median timetoHE was 180days HE grades spanned grade 1 n  6 grade 2 n  8 and grade 3 n  6 9 and 11 cases were recurrent and de novo HE respectively Medication noncomplianceinfection was implicated in HE in 920 45 cases Medical therapy addressed HE in 1820 90 cases however HE still resulted in 39 hospitalizations among 13 patients and median time to first hospitalization was 75days Shunt reduction was necessary in 2 10 cases of medically refractory HE The incidence of HE after VCX TIPS is high Though HE symptoms may be medically controlled hospitalization rates are high and shunt reduction may be necessary The incidence of HE after VCX TIPS is high Though HE symptoms may be medically controlled hospitalization rates are high and shunt reduction may be necessaryCadmium is a highly toxic environmental pollutant which through enhancement of reactive oxygen species ROS production triggers oxidative stress to the cell Cell growth a fundamental feature of all living organisms is closely connected to the cell shape and homeostasis As these processes largely depend on cell fitness status and environmental conditions we have analyzed the impact of different cadmium concentrations and the effect of ascorbic acid ascorbate AsA supplementation on cell growth parameters cell morphology and ionome balance maintenance in Schizosaccharomyces pombe We show that cadmium causes membrane lipid peroxidation resulting in cell shape alterations leading to growth impairment and through mineral elements disequilibrium affects ionome homeostasis in a dose and timedependent manner AsA recognized as one of the most prominent antioxidants when overdosed displays considerable prooxidant activity though precise dosing of its supplementation is desired We present here that AsA under efficacious concentration largely improves cell condition affected by cadmium