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Dry cured ham named Speck is a typical Italian product with consolidated processing techniques and specific quality parameters It has gained importance in the international market after obtaining the Protected Geographical Indication Recent studies indicate that dietary plant extracts in pig may affect quality of processed meats but there are no data on their effect on Speck Consequently the effects of dietary supplementation with antioxidant mixture AOX containing vitamin E and polyphenols in pigs on the nutritional characteristics volatile compounds sensory properties and consumers preference of Speck were evaluated The Speck weight loss during seasoning was lower in the AOX group while products quality parameters were not affected by dietary treatments Alcohol and terpenes concentrations were lower P 005 in the AOX samples than the control Sensory profile revealed slight differences P 005 in Speck salty and sweet taste whereas the consumer tests showed a higher P 005 preference with mean score of seven for Speck from pigs fed AOX Our results provide new insights on the quality parameters of Speck Dietary integration with antioxidant mixture decreased Speck weight losses during seasoning Volatile compounds concentrations and sensory profile were slightly affected by dietary treatment The consumer test revealed that dietary antioxidants increased the overall preference for Speck and can potentially increase its consumption 2020 Society of Chemical Industry Our results provide new insights on the quality parameters of Speck Dietary integration with antioxidant mixture decreased Speck weight losses during seasoning Volatile compounds concentrations and sensory profile were slightly affected by dietary treatment The consumer test revealed that dietary antioxidants increased the overall preference for Speck and can potentially increase its consumption 2020 Society of Chemical IndustryAcute intoxicationtype inborn errors of metabolism ITIEM such as urea cycle disorders and nonacute ITIEM such as phenylketonuria have a major impact on paediatric patients life Patients have to adhere to a strict diet but may face neurocognitive impairment and in acute diseases metabolic decompensations nevertheless Research on the subjective burden of ITIEM remains sparse Studies with appropriate sample sizes are needed to make valid statements about healthrelated quality of life HrQoL in children and adolescents with ITIEM Six international metabolic centres contributed selfreports and proxy reports of HrQoL assessed with the Paediatric Quality of Life Inventory to the final data set n 251 patients age range 23188 years To compare HrQoL of the patient sample with norm data and between acute and nonacute ITIEM t tests were conducted To examine the influence of child age sex diagnosis and current dietary treatment on HrQoL multiple linear regression analyses were conducted Selfreports and proxy reporst showed significantly lower HrQoL total scores for children with ITIEM compared to healthy children Current dietary treatment significantly predicted lower proxy reported total HrQoL Children with nonacute ITIEM reported significantly lower psychosocial health and emotional functioning than children with acute ITIEM The patient sample showed significantly impaired HrQoL and a diet regimen remains a risk factor for lower HrQoL Differences in HrQoL between acute and nonacute ITIEM subgroups indicate that factors beyond symptom severity determine the perception of disease burden Identifying these factors is of crucial importance to develop and implement appropriate interventions for those in need Peripartum seizures remain a leading cause of maternal morbidity and mortality worldwide Therefore recognition of highrisk individuals is essential We aimed to determine the rate and identify risk factors for postpartum seizureepilepsy readmissions In this retrospective cohort study the Nationwide Readmissions Database was used to identify index admissions for delivery and readmissions for seizures in the year 2013 defined by International Classification of Disease Ninth Revision Clinical Modification codes for epilepsy convulsions and eclampsia in the primary diagnostic position Logistic regression analysis was used to examine 30day readmission for seizures as well as associations between demographic medical psychiatric and pregnancyrelated factors There were 1633714 index admissions for delivery with a 30day readmission rate for seizuresepilepsy of 1969 per 100000 index admissions The mean age of index participants was 286 years SD 58 Postpartum 30day readmissions for eor seizureassociated complications Readmissions for seizures are fortunately rare but are important to minimize given morbidity and mortality Most seizure readmissions occurring within 30 days postpartum were coded as eclampsia rather than convulsions or preexisting epilepsy These findings suggest that early identification of women with preeclampsia and eclampsia may play a role in the prevention of postpartum seizures Women with these risk factors should be identified to optimize care and monitored closely for seizureassociated complicationsThe electric organ of the mormyrid weakly electric fish Campylomormyrus rhynchophorus Boulenger 1898 undergoes changes in both the electric organ discharge EOD and the light and electron microscopic morphology as the fish mature from the juvenile to the adult form Of particular interest was the appearance of papillae surface specializations of the uninnervated anterior face of the electrocyte which have been hypothesized to increase the duration of the EOD In a 245 mm long juvenile the adult electric organ EO was not yet functional and the electrocytes lacked papillae A 40 mm long juvenile which produced a short biphasic EOD of 13 ms duration shows small papillae average area 136 μm2 selleck In contrast the EOD of a 79 mm long juvenile was triphasic The large increase in duration of the EOD to 232 ms was accompanied by a small change in size of the papillae average area 159 μm2 Similarly a 150 mm long adult produced a triphasic EOD of comparable duration to the younger stage 247 ms but featured a prominent increase in size of the papillae average area 402 μm2