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Mesothelioma and Non Asbestos Exposure Mesothelioma most commonly develops in the lining of the lungs pleura and abdomen peritoneum The rare cancer may also form in the hearts lining pericardium or testes Asbestos exposure is a major risk factor for mesothelioma However some people diagnosed with mesothelioma may not have an asbestosrelated history Exposure to Asbestos Asbestos a mineral of natural origin was utilized in the past for industrial and construction products around the globe People who worked in asbestos industries handled the substance on a regular basis and were at risk of exposure Asbestos fibres can lodge in the lungs and cause lung diseases This is known as asbestosis Over time these fibers that are trapped in the lungs may cause mesothelioma Asbestos is also inhaled or ingested and the risk of developing mesothelioma and other asbestosrelated illnesses increases depending on the duration and amount of exposure Most cases of mesothelioma stem from exposure to occupational toxins Asbestos was utilized in many trades including construction insulation and electrical work as well as automobile maintenance and pipefitting These trades are typically predominantly maledominated and as a result mesothelioma cases involving males account for 7580 percent of all cases reported However the gradual elimination of asbestos in the United States and other firstworld countries has reduced exposure to asbestos on the job This has resulted in an increase in cases with occupational exposure becoming more common Nonoccupational mesothelioma can develop when asbestos is released from the workplace environment or in the home or school environment It can also be caused by secondhand exposure like when a family member wears the work clothes of an asbestos worker who has been exposed Those who experience this type of exposure might experience symptoms like breathing problems or chest pain which is often mistaken for lung or heart conditions Certain studies have linked mesothelioma to nonoccupational exposure but the results differ Many of these studies were conducted on a limited sample size and the betweenstudy the degree of heterogeneity is high Further research is needed to confirm the links between mesothelioma and exposure to nonoccupational substances People who have experienced nonoccupational asbestos exposure should speak with their doctor about their asbestos background They should request mesothelioma testing in the event of concerns and ask for an appointment with a specialist Specialists in mesothelioma can provide the most effective treatment and care to improve a patients prognosis They will look over medical records and conduct imaging tests to identify mesothelioma They will also provide guidance on how to file a mesothelioma suit to obtain compensation from an asbestos trust fund Secondhand Exposure While asbestos exposure is the main cause of mesothelioma its not the only way to develop this disease In fact theres some evidence that shows that people can develop mesothelioma even though they never directly handled asbestos or worked in an industry with asbestosrelated activities This is referred to as secondary asbestos exposure or nonoccupational asbestos exposure Asbestos fibers are extremely small and they can stick to hair clothing skin and other surfaces Workers can carry dangerous fibers in their work clothes home and transmit them to family members The asbestos fibers that are scattered around can be swallowed or inhaled leading to mesothelioma This form of mesothelioma is more prevalent in women and it usually occurs in the lung However it could also be found in the abdomen and chest wall The most commonly reported sign is a shortness of breath dyspnea and it may be associated with other symptoms such as fluid in the lungs or a swelling in the scrotum Pleural mesothelioma is a name given to mesothelioma which is found in the lungs Mesothelioma that affects the stomach or chest wall is called mesothelioma peritoneal This kind of mesothelioma may cause a variety of symptoms including abdominal pain difficulty breathing and constipation According to numerous studies individuals who have not been exposed to asbestos in the workplace may still develop mesothelioma due to exposure from secondhand sources The people who were affected usually lived with someone who was exposed to asbestos They may have touched the workers clothing or they might have had other contact with asbestos Veterans are at a high risk of mesothelioma because asbestos was extensively used in military bases vehicles and ships The Navy is particularly at risk since asbestos was used to insulate the hull of the ship and to fireproof gun turrets Asbestos was also frequently taken home by sailors after their duties aboard ships that had been infected with asbestos Environmental Exposure Mesothelioma is linked to various substances However the disease is often linked to exposure to asbestos carson asbestos lawsuit is a mineral that occurs naturally was used in manufacturing for a number of years The mineral is resistant to heat and strong which makes it suitable for insulation brakes flooring shingles and other items When asbestos is broken down it creates dust that can be inhaled or swallowed The asbestos fibers can stay in the lungs or stomach for years and trigger mesothelioma symptoms The most frequent mesothelioma symptoms are chest pain abdominal discomfort and trouble breathing Asbestos exposure can cause these symptoms to persist for up to 60 years These symptoms could be mistaken for other diseases therefore it is important to see your doctor if you exhibit these symptoms It is also important to tell your doctor about your past history of asbestos This can prevent a wrong diagnosis and ensure that you receive the right treatment The most frequent mesothelioma patients from asbestos exposure are those who worked directly with it but it is possible for loved ones to be affected This is known as secondary exposure Family members may inhale or swallow asbestos fibers on a workers clothes shoes or other tools They could also be exposed to the particles on their clothing or hair It is for this reason that mesothelioma sufferers as well as their families must always wash their clothes in a clean manner after working with asbestos There is a huge body of literature showing an association between nonasbestos and mesothelioma However there are still no conclusive conclusions regarding the role of other agents For instance there is some evidence that the zeolites erionite and chlorosotile can cause mesothelioma Erionite is found in soil and rocks in some regions of Turkey where pleural mesothelioma rates are high The study of the connection between asbestos and mesothelioma continues Funnel plots suggest the possibility of bias in publications and there is a significant level of heterogeneity among studies It is clear that asbestos exposure is the biggest mesothelioma risk factor Genetics The rare disease mesothelioma occurs when malignant cells of mesothelium multiply uncontrollably and invade surrounding tissues It can also expand throughout the body through traversing the lymphatic system or bloodstream and impacting other organs While asbestos is the main cause of mesothelioma it isnt the sole risk factor Other environmental and genetic factors can cause the condition In some cases mesothelioma is seen in people who were not exposed to asbestos They are known as nonoccupational victims of mesothelioma They were usually exposed indirectly by the handling of contaminated clothing or household items by someone who was exposed asbestos in their home It is possible to be diagnosed with mesothelioma following inhaling asbestos fibers from the clothing of a family member Research has shown that these types of mesothelioma patients tend to have longer periods of latency and are more likely to be diagnosed in wives rather than husbands Scientists are studying the possibility that genetic predispositions to mesothelioma could play a role in its development Recent studies have revealed that the mutation of BAP1 genes increases the risk of mesothelioma in asbestosexposed patients This finding is important because it could lead to improved screening methods for those who are at a high risk of developing mesothelioma Researchers have identified a variety of genes that are related to mesothelioma Certain of these genes are involved in reducing tumor growth and are often altered or mutated in mesothelioma sufferers These genes include the massive homolog of tumor suppressor 2 LATS2 and the NF2 A family history of the disease increases the risk This is because some genes like the BAP1 one can be inherited from an individual parent Veterans have the highest mesothelioma rate when compared to other occupational categories because asbestos was heavily used in the military People who were in the Navy and on ships specifically were at greatest risk because of the extensive exposure to asbestos in fireproofing insulation materials and shipbuilding

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