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The activity of platinumcopper catalysts in the MOR and the currentvoltage characteristics of the H2Air protonexchange membrane fuel cell MEAs measured in the process of their life tests were much higher than those of the PtC catalystsIn the scientific landscape there is a growing interest in defining the role of several biomolecules and humoral indicators of the aging process and in the modifications of these biomarkers induced by physical activity and exercise The main aim of the present narrative review is to collect the available evidence on the biohumoral indicators that could be modified by physical activity PA in the elderly Online databases including Pubmed Web of science Medline and Scopus were searched for relevant articles published in the last five years in English Keywords and combination of these used for the search were the following biological indicators markers physical activity and elderly Thirtyfour papers were analyzed for inclusion Twentynine studies were included and divided into four categories cardiovascular CV biomarkers metabolic biomarkers inflammatory markersoxidative stress molecules and other markers There are many distinct biomarkers influenced by PA in the elderly with promising results concerning the metabolic and CV indexes as a growing number of studies demonstrate the role of PA on improving parameters related to heart function and CV risk like atherogenic lipid profile Furthermore it is also a verified hypothesis that PA is able to modify the inflammatory status of the subject by decreasing the levels of proinflammatory cytokines including interleukin1 IL1 interleukin6 IL6 and tumor necrosis factoralpha TNFα PA seems also to be able to have a direct effect on the immune system There is a strong evidence of a positive effect of PA on the health of elderly people that could be evidenced and quantified by the modifications of the levels of several biohumoral indicatorsCarnitine palmitoyltransferase CPT catalyzes the transfer of long and mediumchain fatty acids from cytoplasm into mitochondria where oxidation of fatty acids takes place Deficiency of CPT enzyme is associated with rare diseases of fatty acid metabolism CPT is present in two subforms CPT I at the outer mitochondrial membrane and carnitine palmitoyltransferase II CPT II inside the mitochondria Deficiency of CPT II results in the most common inherited disorder of longchain fatty acid oxidation affecting skeletal muscle There is a lethal neonatal form a severe infantile hepatocardiomuscular form and a rather mild myopathic form characterized by exerciseinduced myalgia weakness and myoglobinuria Total CPT activity CPT I CPT II in muscles of CPT IIdeficient patients is generally normal Nevertheless in some patients not detectable to reduced total activities are also reported CPT II protein is also shown in normal concentration in patients with normal CPT enzymatic activity However residual CPT II shows abnormal inhibition sensitivity towards malonylCoA Triton X100 and fatty acid metabolites in patients Genetic studies have identified a common pSer113Leu mutation in the muscle form along with around 100 different rare mutations The biochemical consequences of these mutations have been controversial Hypotheses include lack of enzymatically active protein partial enzyme deficiency and abnormally regulated enzyme The recombinant enzyme experiments that we recently conducted have shown that CPT II enzyme is extremely thermoliable and is abnormally inhibited by different emulsifiers and detergents such as malonylCoA palmitoylCoA palmitoylcarnitine Tween 20 and Triton X100 Here we present a conceptual overview on CPT II deficiency based on our own findings and on results from other studies addressing clinical biochemical histological immunohistological and genetic aspects as well as recent advancements in diagnosis and therapeutic strategies in this disorderWhile the number of casualties and amount of property damage caused by fires in urban areas are increasing each year studies on their automatic detection have not maintained pace with the scale of such fire damage Camerabased fire detection systems have numerous advantages over conventional sensorbased methods but most research in this area has been limited to daytime use However nighttime fire detection in urban areas is more difficult to achieve than daytime detection owing to the presence of ambient lighting such as headlights neon signs and streetlights Therefore in this study we propose an algorithm that can quickly detect a fire at night in urban areas by reflecting its nighttime characteristics It is termed ELASTICYOLOv3 which is an improvement over the existing YOLOv3 to detect fire candidate areas quickly and accurately regardless of the size of the fire during the preprocessing stage To reflect the dynamic characteristics of a nighttime flame N frames are accumulated to create a temporal firetube and a histogram of the optical flow of the flame is extracted from the firetube and converted into a bagoffeatures BoF histogram The BoF is then applied to a random forest classifier which achieves a fast classification and high classification performance of the tabular features to verify a fire candidate Based on a performance comparison against a few other stateoftheart fire detection methods the proposed method can increase the fire detection at night compared to deep neural network DNNbased methods and achieves a reduced processing time without any loss in accuracyAutophagy is a highly conserved intracellular degradation pathway that breaks down damaged macromolecules andor organelles It is involved in plant development and senescence as well as in biotic and abiotic stresses However the autophagy process and related genes are largely unknown in citrus In this study we identified 35 autophagyrelated genes CsATGsautophagyrelated genes ATGs of Citrus sinensis Cs in a genomewide manner from sweet orange Citrus sinensis check details Bioinformatic analysis showed that these CsATGs were highly similar to Arabidopsis ATGs in both sequence and phylogeny All the CsATGs were randomly distributed on nine known 28 genes and one unknown 7 genes chromosomes Ten CsATGs were predicted to be segmental duplications Expression patterns suggested that most of the CsATG were significantly up or downregulated in response to drought cold heat salt mannitol and excess manganese copper and cadmium stresses In addition two ATG18 members CsATG18a and CsATG18b were cloned from sweet orange and ectopically expressed in Arabidopsis